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Interventions › methylphenidate

methylphenidate

AKA: ritalin, concerta

Methylphenidate is a central nervous system (CNS) stimulant medication used to treat attention deficit hyperactivity disorder (ADHD) and, to a lesser extent, narcolepsy. It is a primary medication for ADHD. It may be taken by mouth or applied to the skin, and different formulations have varying durations of effect. It is also used as an athletic performance enhancer and cognitive enhancer, and recreationally as an aphrodisiac and euphoriant.

Studies

1

Participants

113

Outcomes

1

Last updated

6 days ago

Used to treat

Effect size

The effect size tells you the magnitude of the effect being studied. There are several measures of effect size, but GlacierMD uses Hedges g.

g > 1.2

Huge

0.8 < g ≤ 1.2

Very large

0.5 < g ≤ 0.8

Large

0.2 < g ≤ 0.5

Medium

0.01 < g ≤ 0.2

Small

g < 0.01

Very small

Evidence rating

The evidence rating describes how well this particular research question is supported by evidence.

This topic is supported by lots of consistent, high-quality evidence

This topic is supported by consistent, high-quality evidence

There's some evidence for this topic, but it's limited or inconsistent

There's little evidence supporting this topic

This topic has little or no evidence

Risk rating

The risk rating summarizes the risks associated with an intervention.

This intervention has serious side effects that are relatively common

This intervention has serious side effects

This intervention has relatively common side effects

This intervention has side effects

This intervention has rare side effects

gScore

The gScore is a composite score that combines:

Research

The total amount of research conducted on this topic. Higher-quality research is weighted more heavily than lower-quality research.

Efficacy

The observed effect size. This is normalized between different outcomes using Hedges g.

Risk

The risk of using this treatment, including side effects, addictiveness, and FDA warnings.

Condition

Outcome

gScore

▲

Research

▲

Effect size

▲

Chronic fatigue syndrome

Myalgic encephalomyelitis

Fatigue self-rating

2.4

0.45

View research ›

Risks

Boxed warning

WARNING: ABUSE AND DEPENDENCE C N S stimulants, including methylphenidate hydrochloride extended-release capsules , other methylphenidate-containing products, and amphetamines, have a high potential for abuse and dependence. Assess the risk of abuse prior to prescribing, and monitor for signs of abuse and dependence while on therapy [see Warnings and Precautions ( 5.1 ), Drug Abuse and Dependence ( 9.2 , 9.3 )] . WARNING: ABUSE AND DEPENDENCE See full prescribing information for complete boxed warning. CNS stimulants, including methylphenidate hydrochloride extended-release capsules , other methylphenidate-containing products, and amphetamines, have a high potential for abuse and dependence ( 5.1 , 9.2 , 9.3 ). Assess the risk of abuse prior to prescribing, and monitor for signs of abuse and dependence while on therapy ( 5.1 , 9.2 ).

Side effect

Incidence

appetite loss

10%

insomnia

10%

mood swings

confusion

back pain

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Interventions › methylphenidate

methylphenidate

Studies

1

Participants

113

Outcomes

1

Last updated

6 days ago

Used to treat

Effect size

Evidence rating

Risk rating

gScore

Risks

Company

Legal

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